Fematrope® Research Summary
Rosemarinus officinalis (25% Ursolic Acid)
Promising research has shown it to prevent muscle atrophy (muscle wasting/muscle loss) and to increase muscle hypertrophy (muscle growth) due to its naturally occurring Ursolic Acid content1
Ursolic acid has been shown to promote skeletal muscle rejuvenation through satellite cell proliferation2
Apigenin
Naturally occurring compound found in parsley, but also in smaller quantities in celery, oranges, grapefruit, and chamomile3
Shown to act as an anti-inflammatory agent for reducing inflammation related issues4
Research has shown it to not only enhance muscle hypertrophy but to also prevent muscle breakdown5
AstraGin® (Astragalus membranaceous and Panax notoginseng (root) Extract)
Amplifies the absorption of ingredients including peptides, amino acids, fatty acids, vitamins, and phytonutrients by up-regulating the absorption specific mRNA and transporters6
Shown to rejuvenate ulcerated and damaged intestinal walls and reduce intestinal submucosa inflammation7
Supports digestive system by maintaining a healthy microbiota population via mending ulcerated and damaged intestinal epithelial cell surfaces for the microbiota to populate8
Helps support stronger immune functions by mending ulcerated epithelial cells and reducing the inflammation in intestines7
References
- Bahrami S. Ursolic acid regulates aging process through enhancing of metabolic sensor proteins level. Biomed Pharmacother. 2016;82:8-14. doi:10.1016/j.biopha.2016.04.047
- Bakhtiari N. Short-term ursolic acid promotes skeletal muscle rejuvenation through enhancing of SIRT1 expression and satellite cells proliferation. Biomed Pharmacother. 2016;78:185-196. doi:10.1016/j.biopha.2016.01.010
- He X. Protective role of apigenin in cisplatin-induced renal injury. Eur J Pharmacol. 2016;789:215-221. doi:10.1016/j.ejphar.2016.07.003
- Leyva-Lopez N. Flavonoids as Cytokine Modulators: A Possible Therapy for Inflammation-Related Diseases. Int J Mol Sci. 2016;17(6). doi:10.3390/ijms17060921
- Jang YJ. Apigenin enhances skeletal muscle hypertrophy and myoblast differentiation by regulating Prmt7. Oncotarget. 2017;8(45):78300-78311. doi:10.18632/oncotarget.20962
- Chang T. Effect of ginsenosides on glucose uptake in human Caco-2 cells is mediated through altered Na+/glucose cotransporter 1 expression. J Agric Food Chem. 2007;55(5):1993-1998. doi:10.1021/jf062714k
- Lee S. Astragaloside II promotes intestinal epithelial repair by enhancing L-arginine uptake and activating the mTOR pathway. Sci Rep. 2017;7(1). doi:10.1038/s41598-017-12435-y
- Wang H. Bioactivity enhancement of herbal supplements by intestinal microbiota focusing on ginsenosides. Am J Chin Med. 2011;39(6):1103-1115. doi:10.1142/S0192415X11009433