“GET READY TO FEEL LIKE YOUR MUSCLES ARE GOING TO EXPLODE!!”
One of the worst feelings in the world is not being able to get a good pump!! Your muscles feel flat and deflated, and you can’t get a pump. Dragon Pharma Labs
“GET READY TO FEEL LIKE YOUR MUSCLES ARE GOING TO EXPLODE!!”
One of the worst feelings in the world is not being able to get a good pump!! Your muscles feel flat and deflated, and you can’t get a pump. Dragon Pharma Labs MR. VEINZ is a unique combination of ingredients designed to ignite vasodilation (i.e. blood flow), increase vascularity, and enhance recovery. Mr. VEINZ consists of a Pump and Strength Matrix consisting of Hydromax glycerol, sodium nitrate, creatine, AAKG, and beta-alanine to increase nitric oxide as well as increasing strength and performance. The second component consists of an Energy and Focus Matrix consisting of caffeine, DMHA, and theacrine to enhance mental focus and increase energy to train. Mr. VEINZ was scientifically designed to do the following:
- Increases Vasodilation: Your veins are like a garden hose, it you have a kink in the garden hose, less water is going to flow thru the nozzle and you are going to have less blood flow and muscle pumps. MR. VEINZ opens up blood vessels so you get the most intense pumps you have ever had in the gym. Get ready to feel like your muscles are balloons being filled with air at high pressure!! Enhanced blood flow will also drive oxygen rich blood into your circulation, resulting in enhanced health. Furthermore, MR. VEINZ increases muscle hydration so your muscle are going to feel “full” and “pumped.”
- Greater Nutrient Delivery to Your Muscles: Enhanced blood flow allows for greater nutrient delivery of amino acids, glucose, and other growth factors into muscle cells.
- Greater Strength and Muscular Endurance: The cutting-edge ingredients in MR. VEINZ will result in greater increases in muscular strength and endurance. This means that not only will you use greater weight in the gym to build muscle, but will also be able to increase the number of repetitions each set per training session resulting in enhanced muscle growth.
Supports more than 500 enzymatic reactions that play key roles in metabolism and energy production. Niacin supports muscle growth and gives enhances muscle pumps. Niacin also enhances Growth Hormone production. Its benefits go beyond athletic performance. Niacin also increases good cholesterol (HDL) and reduces bad cholesterol (LDL).
Pump and Strength Matrix
Beta Alanine- 2000 mg
Beta-alanine is converted into the molecule carnosine, which acts to buffer lactic acid in the body. Beta Alanine also has several health benefits such as being: anti-aging, an antioxidant, and also protects against destructive advanced glycation end products. Beta-alanine shows the most promise for short high-intensity exercises (such as sprinting, rowing, and weightlifting). Chronic use of beta-alanine is also associated with increases in lean muscle mass. For example:
- One 8-week study supplemented beta-alanine to collegiate wrestlers and American-football players. Football players using beta-alanine group gained more lean mass (~2.1 lbs.) than the placebo group (~1.1lbs.) and gained less fat mass (0.88%) than the placebo group (0.1%)5. Among the wrestlers, both the beta-alanine groups and the placebo group lost fat, but the beta-alanine group saw an increase in lean mass (~1.1 lbs.), while the placebo group saw a decrease (-.98 lbs.). Consequently, the beta-alanine group lost less total mass than the placebo group (3.2 lbs.)
- In a 6-week study on athletic women performing high-intensity exercise, the beta-alanine group saw an increase in lean mass, while the control group did not. Beta Alanine is going to allow for more repetitions to be completed and more exercise volume, which leads to greater muscle growth. Beta Alanine seems to work synergistically with creatine. One 10-week study in collegiate football players reported that, compared to creatine alone, a combination of creatine and beta-alanine resulted in greater lean mass gain and fat mass loss.
CREATINE MONOHYDRATE- 1,000 MG
Creatine helps build muscle faster due to increased production and delivery of ATP in muscle cells. Creatine enables you to recover quicker between sets and has consistently been shown to enhance sports performance. This also provides more energy to the muscles, providing a more intense workout. There are many forms of creatine, but creatine monohydrate has more research to support its effectiveness than any other form. Creatine monohydrate has been proven to be the most effective form of creatine by leading sports authorities such as the International Society for Sports Nutrition.
The anabolic effects of creatine are well documented:
- Creatine causes “cell volumization” which promotes a cellular anabolic state associated with less protein breakdown and increased DNA synthesis.
- Creatine is also well documented to increase lean muscle mass as well. One study supplementing creatine for 8 weeks in conjunction with resistance exercise resulted in a greater increase in lean mass and power relative to placebo at 4 and 8 weeks, furthermore, the muscle inhibiting gene myostatin in serum decreased to a greater extent with creatine (around 17% at 8 weeks, derived from graph) than it did with placebo (approximately 7%).
- Creatine supplementation can also increase muscle fiber size independent of protein synthesis, as increasing water content in muscle cells increases their diameter. After creatine supplementation, was ingested type I, IIa and IIx fibers increased in diameter by 9%, 5%, and 4% respectively.
- Creatine has been found to increase the anabolic growth factor IGF-1.
- Creatine increases satellite cell which are essential for muscle growth and recuperation.
There are quite a few myths regarding creatine. Some of the more common myths are: creatine needs to be loaded, creatine causes muscle cramps, you must “cycle off” creatine, creatine needs to be ingested with glucose, and creatine causes kidney problems are all myths!!
L-Arginine Alpha-Ketoglutarate (AAKG)- 1000 mg
Arginine alpha-ketoglutarate (AAKG) is a dietary supplement used by athletes and bodybuilders to improve sports performance, reduce muscle fatigue, and enhance recovery. AAKG also regulates amino acid synthesis, energy production, and formation of free radicals. It functions as a messenger molecule in many chemical reactions in the body. Arginine alpha-ketoglutarate is formed when two arginine molecules combine with one molecule of alpha-ketoglutarate.
One examined the effects of AAKG supplementation during training on body composition and training adaptations in experienced gym men. Subjects taking AAKG had greater changes in bench press one repetition maximum. Not just a little increase, but a lot!! AAKG supplementation added an average of more than 13 pounds to bench press max over placebo. Another study in older adults found that AAKG could increase anaerobic performance on the cycle and improve bench press strength. The vasodilatory properties of arginine may facilitate an increase in oxygen delivery, which helps meet the increased demands caused by exercise. AAKG stimulates the production of the anabolic hormones’ insulin-like growth factor-1 and growth hormone. As a precursor of glutamine, AAKG is a molecule with high potential in the treatment of states with increased protein catabolism, such as recovery after trauma, severe infections, and burns, or after surgeries. For example, in people who underwent surgical trauma, supplementing AAKG in a controlled trial prevented muscle breakdown and increased protein synthesis.
The human body is made up of 60~70 % of water. Exercise in hot and humid environments can cause intense sweating which can deplete up to a liter of water (or more). Hydromax Glycerol is a patented form of glycerol transforms your cells into ultra-absorbent sponges that soak up extra water. Glycerol has also been shown to help athletes store extra water, delaying the need for hydration. This suggests improved efficiency in exercise, thermoregulation and decreased physiological stress. The cells soak up water which improves hydration resulting in greater muscle pumps and fullness. HydroMax™ is a highly-concentrated form of powdered glycerol in a proprietary blend of glycerol and silica. Glycerol was originally used as an endurance supplement because of its ability to prevent dehydration, it later was found its way into the bodybuilding community as a pre-workout muscle pump ingredient. Hydromax Glycerol increases the plasma volume within the muscles which increases muscular size during physical exercise.
HydroMax glycerol is easily absorbed and distributed throughout the intracellular space, increasing the concentration of fluid in the blood and tissues. In particular, it increases the concentration of fluid in blood and intracellular tissues to a point of hyperhydration. Dehydration has been shown to acutely decrease performance; however, Hydromax Glycerol increase exercises performance by keeping your muscle hydrated, lowering physical stress, and prolonging muscle endurance. Furthermore, Hydromax glycerol results in faster recovery by enhancing amino acid uptake in muscle which aids in better muscle growth. Glycerol is also often used in conjunction with other “pump” ingredients, such as creatine, taurine, agmatine, “nitric-oxide-enhancing” extracts and botanical dietary nitrates, to further enhance the benefits of these bioactive compounds.
Sodium Nitrate 250 mg
Nitric oxide (NO) is a signaling molecule involved in many cell processes, including vasodilation, or widening of the blood vessels. Wider blood vessels increase the delivery of nutrients and oxygen to the working muscles during exercise, enhancing muscle growth and recovery. Nitrates are supplied in the diet through the consumption of vegetables and drinking water, with vegetables contributing more than 85 percent of the total dietary intake of nitrate. A form of nitrate that uses the reverse route of nitric oxide to increase its production and blood flow by expanding the blood vessels. Nitrates are one of the most powerful NO-boosting ingredients around. Plus, nitrates also support heart health by reducing blood pressure and guarding against endothelial dysfunction.
Energy and Focus Matrix
Caffeine Anhydrous - 100 mg
CAFFEINE Anhydrous s the stimulant that acts in all central nervous system, this way it increases the sensation of alertness and mental activity, besides improving the body's response in training. Caffeine’s actions on the CNS occur primarily on the major upper brain centers, resulting from this action, a state of alertness and increased mental activity. Acutely, caffeine ingestion increases adrenaline and noradrenaline levels in the body in a dose-dependent manner. The increase of metabolic rate may be dose-dependent and be somewhat related to adrenaline and noradrenaline release. Studies show that a dose of caffeine will improve strength and athletic performance. Caffeine reduces the perception of pain in conjunction with increasing calcium release in muscle cells, [which can increase muscle power output]. Sub-maximal power output, in the 6-12 rep range, tends to be increased with caffeine as assessed by increased work volume. Another interesting from new research is that caffeine has been implicated in increasing the testosterone response to exercise; testosterone increased 53% as a response to exercise in both groups and a further 12+/-14% with 240mg caffeine.
DMHA - 100 mg
Powerful stimulant that promotes improved energy levels and cognitive function, increased mental focus and improved bronchodilation. 2-amino-5-methylhexane is considered a stimulant that promotes wakefulness. 2-amino-5-methylhexane boosts energy levels, focus, concentration. 2-amino-5-methylhexane works on the brain’s reward system, notably dopamine and norepinephrine, are responsible for exerting many of the common effects that stimulants produce – including enhanced euphoria and wakefulness (alertness), respectively. 2-amino-5-methylhexane is a compound’s whose lipid solubility dramatically increases its ability to pass through the blood-brain barrier where it can exert its focus-enhancing and euphoric effects. In addition, users of 2-amino-5-methylhexane have reported a higher pain threshold and a decreased rate of perceived exertion, thus allowing workouts to extend beyond the point of fatigue.
Theacrine - 25 mg
Increases mental focus during exercise. Theacrine is able to work with caffeine to sustain the cognitive benefits during exercise so you never miss a workout. Theacrine is a brain/nervous system stimulant that became popular in sports nutrition as a pre-workout and fat burner supplement. Theacrine enhances and extends the positive effects of caffeine while minimizing its negative side effects. The chemical structure of theacrine is similar to caffeine, and scientific evidence suggests that it activates similar signaling pathways. theacrine and caffeine are more effective when taken together because caffeine increases the bioavailability and positive effects of theacrine in humans. Theacrine, when combined with caffeine, can also raise dopamine and enhance mood. One study found that when taking theacrine and caffeine together resulted in enhanced energy and mood when compared to either caffeine alone or placebo. It also decreased feelings of lethargy and grogginess.
- INCREASES TRANSPORT OF NUTRIENTS TO MUSCLES
- INCREASES VASCULARIZATION
- INCREASES ENERGY
- INCREASES STRENGTH AND ENDURANCE
- INCREASED MUSCLE PUMPS AND HYDRATION
- Hipkiss AR. On the enigma of carnosine's anti-ageing actions. Exp Gerontol. 2009 Apr;44(4):237-42.
- Hoffman JR, Varanoske A, Stout JR. Effects of β-Alanine Supplementation on Carnosine Elevation and Physiological Performance. Adv Food Nutr Res. 2018;84:183-206.
- Hipkiss AR, Michaelis J, Syrris P. Non-enzymatic glycosylation of the
- dipeptide L-carnosine, a potential anti-protein-cross-linking agent. FEBS Lett.1995 Aug 28;371(1):81-5.
- Derave W, Ozdemir MS, Harris RC, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E. beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. J Appl Physiol (1985). 2007 Nov;103(5):1736-43.
- Kern BD, Robinson TL. Effects of β-alanine supplementation on performance and body composition in collegiate wrestlers and football players. J Strength Cond Res. 2011 Jul;25(7):1804-15.
- Bishop D, Edge J, Davis C, Goodman C. Induced metabolic alkalosis affects muscle metabolism and repeated-sprint ability. Med Sci Sports Exerc. 2004 May;36(5):807-13.
- Walter AA, Smith AE, Kendall KL, Stout JR, Cramer JT. Six weeks of
- high-intensity interval training with and without beta-alanine supplementation for improving cardiovascular fitness in women. J Strength Cond Res. 2010 May;24(5):1199-207.
- Smith AE, Walter AA, Graef JL, Kendall KL, Moon JR, Lockwood CM, Fukuda DH,Beck TW, Cramer JT, Stout JR. Effects of beta-alanine supplementation and high-intensity interval training on endurance performance and body composition in men; a double-blind trial. J Int Soc Sports Nutr. 2009 Feb 11;6:5.
- Hoffman J, Ratamess N, Kang J, Mangine G, Faigenbaum A, Stout J. Effect of creatine and beta-alanine supplementation on performance and endocrine responses in strength/power athletes. Int J Sport Nutr Exerc Metab. 2006 Aug;16(4):430-46.
- Hobson, R. M., Saunders, B., Ball, G., Harris, R. C., & Sale, C. (2012). Effects of β-alanine supplementation on exercise performance: A meta-analysis. Amino Acids, 43(1), 25-37. doi:10.1007/s00726-011-1200-z
- Häussinger D, Lang F. Cell volume and hormone action. Trends Pharmacol Sci.1992 Oct;13(10):371-3.
- Häussinger D, Roth E, Lang F, Gerok W. Cellular hydration state: an important determinant of protein catabolism in health and disease. Lancet. 1993 May 22;341(8856):1330-2.
- Saremi A, Gharakhanloo R, Sharghi S, Gharaati MR, Larijani B, Omidfar K. Effects of oral creatine and resistance training on serum myostatin and GASP-1.Mol Cell Endocrinol. 2010 Apr 12;317(1-2):25-30.
- Safdar A, Yardley NJ, Snow R, Melov S, Tarnopolsky MA. Global and targeted gene expression and protein content in skeletal muscle of young men following short-term creatine monohydrate supplementation. Physiol Genomics. 2008 Jan 17;32(2):219-28.
- Burke DG, Candow DG, Chilibeck PD, MacNeil LG, Roy BD, Tarnopolsky MA, Ziegenfuss T. Effect of creatine supplementation and resistance-exercise training on muscle insulin-like growth factor in young adults. Int J Sport Nutr Exerc Metab. 2008 Aug; 18(4):389-98.
- Louis M, Van Beneden R, Dehoux M, Thissen JP, Francaux M. Creatine increases IGF-I and myogenic regulatory factor mRNA in C(2)C(12) cells. FEBS Lett. 2004 Jan 16; 557(1-3):243-7.
- Cylwik D, Mogielnicki A, Buczko W. L-arginine and cardiovascular system. Pharmacol Rep2005;57:14-22 [review].
- 2. Campbell B, Baer J, Roberts M, et al. Effects of arginine alpha-ketoglutarate supplementation on body composition and training adaptations. Sports Nutrition Review Journal 2004:1(1):S10 [abstract].
- Campbell B, Roberts M, Kerksick C, et al. Pharmacokinetics, safety, and effects on exercise performance of l-arginine alpha-ketoglutarate in trained adult men. Nutrition2006;22:872-81.
- Vacanti T, Campbell B, Baer J, et al. Effects of arginine alpha-ketoglutarate supplementation on markers of catabolism and health status. Sports Nutr Rev J2004;1:S10-S11 [abstract].
- Zdzisińska B, Żurek A, Kandefer-Szerszeń M. Alpha-Ketoglutarate as a Molecule with Pleiotropic Activity: Well-Known and Novel Possibilities of Therapeutic Use. Archivum Immunologiae et Therapiae Experimentalis. 2017;65(1):21-36. doi:10.1007/s00005-016-0406-x.
- Ammarqvist F, Wernerman J, von der Decken A, Vinnars E. Alpha-ketoglutarate preserves protein synthesis and free glutamine in skeletal muscle after surgery. Surgery. 1991 Jan;109(1):28-36.
- Hydromax 65% Glycerol Powder. A UNIQUELY OPTIMIZED, HIGHLY CONCENTRATED POWDERED FORM OF GLYCEROL DELIVERING NEXT-LEVEL HYDRATION AND NEXT-GEN PRODUCT POTENTIAL. Jeremy Bartos, Ph.D.
- Ross ML, Jeacocke NA, Laursen PB, Martin DT, Abbiss CR, Burke LM. Effects of
- lowering body temperature via hyperhydration, with and without glycerol ingestion and practical precooling on cycling time trial performance in hot and humid conditions. J Int Soc Sports Nutr. 2012 Dec 17;9(1):55.
- Beis LY, Polyviou T, Malkova D, Pitsiladis YP. The effects of creatine and glycerol hyperhydration on running economy in well trained endurance runners. J Int Soc Sports Nutr. 2011 Dec 16;8(1):24. doi: 10.1186/1550-2783-8-24.
- Nelson JL, Robergs RA. Exploring the potential ergogenic effects of glycerol hyperhydration. Sports Med. 2007;37(11):981-1000. Review.
- Lyons TP, Riedesel ML, Meuli LE, Chick TW. Effects of glycerol-induced
- hyperhydration prior to exercise in the heat on sweating and core temperature. Med Sci Sports Exerc. 1990 Aug;22(4):477-83.
- Gangolli SD, van den Brandt PA, Feron VJ, et al. Nitrate, nitrite and N-nitroso compounds. Eur J Pharmacol. 1994; 292(1):1-38.
- Jones AM. Dietary nitrate supplementation and exercise performance. Sports Med. 2014; 44(Suppl 1):S35-45.
- Nitrate in Vegetables – Scientific Opinion of the Panel on Contaminants in the Food Chain. European Food Safety Authority,
- Sindler, Amy L. et al; “Nitrite Supplementation Reverses Vascular Endothelial Dysfunction and Large Elastic Artery Stiffness with Aging”; Aging cell 10.3 429–437; 2011;
- Larsen, F; “Effects of dietary nitrate on oxygen cost during exercise”; Acta Physiol (Oxf). 2007 Sep;191(1):59-66;
- SODIUM NITRATE. National Center for Biotechnology Information. PubChem Compound Database, S National Library of Medicine, 2005.
- Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K, Jéquier E.Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. Am J Clin Nutr. 1980 May;33(5):989-97.
- Bellar D, Kamimori GH, Glickman EL. The effects of low-dose caffeine on perceived pain during a grip to exhaustion task. J Strength Cond Res. 2011 May;25(5):1225-8.
- Davis JK, Green JM. Caffeine and anaerobic performance: ergogenic value and mechanisms of action. Sports Med. 2009;39(10):813-32.
- Astorino TA, Rohmann RL, Firth K. Effect of caffeine ingestion on one-repetition maximum muscular strength. Eur J Appl Physiol. 2008 Jan;102(2):127-32.
- Paton CD, Lowe T, Irvine A. Caffeinated chewing gum increases repeated sprint performance and augments increases in testosterone in competitive cyclists. Eur J Appl Physiol. 2010 Dec;110(6):1243-50.
- Wise, R., & Bozarth, M; “Brain Mechanism of Drug Reward and Euphoria”; Journal of Psychiatric Medicine, 3(4): 445-460; 1985.
- Millerm G; “The emerging role of Trace Amine Associated Receptor 1 in the Functional Regulation of Monoamine Transporters and Dopaminergic Activity”; Journal of Neurochemistry, 116(2): 164-176; 2011.
- Sullivan, J., & Tipton, K; “The interactions of monoamine oxidase with some derivatives of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)”; Journal of Neural Transmission, 29: 269-277; 1990.
- He H, Ma D, Crone LB, Butawan M, Meibohm B, Bloomer RJ, Yates CR. Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans. J Caffeine Res. 2017 Sep 1;7(3):95-102.
- Kuhman DJ, Joyner KJ, Bloomer RJ. Cognitive Performance and Mood Following Ingestion of a Theacrine-Containing Dietary Supplement, Caffeine, or Placebo by Young Men and Women. Nutrients. 2015 Nov 19;7(11):9618-32.